Toward experiment-guided AlphaFold: Researchers overcome AI tool's single-conformation limitation
AlphaFold can now be guided with experimental data to predict multiple protein conformations instead of collapsing heterogeneous structures into a single dominant shape. Researchers at ISTA developed this approach by incorporating experimental conditions that alter local protein structure, as published in Nature Biotechnology.
Read full story →Mosquitoes are rapidly activating enzymes against common insecticide, researchers warn
Mosquitoes are developing enzyme activity that provides resistance to commonly used insecticides through biochemical and genetic changes. Public health programs have historically depended on these chemicals for mosquito management, making control increasingly difficult as populations gain survival advantages.
The cost of memory: How organisms balance thinking and sensing
Organisms must balance memory usage against its energy costs when making decisions. A study examined how much biological resources animals and cells expend to store and retrieve information for survival tasks like foraging.
First Arctic Ocean 2050 expedition on its way to the North Pole
A research vessel with 30 scientists and 20 crew members departed from Longyearbyen on July 23 to study the Arctic Ocean over 50 days as part of the Polhavet 2050 program. The expedition aims to reach the North Pole while conducting research during this Arctic voyage.